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We speculated that anti-LOX remodeled the penile tunica albuginea by inhibiting the crosslinking of collagen and elastin, thereby reducing the tensile strength of collagen and elasticity of elastin.17,18,19 Chronic traction has been previously applied to lengthen limbs using the Ilizarov technique.39 Mechanical stressing restructured collagen and allowed its stretching in Dupuytren's disease tissue,23,40 while the traction device was reported to lengthen the penis in some noncontrolled case studies.6,24,25 A recent animal study also showed that the traction device and VD can exert a tissue remodeling effect to correct penile curvature.41 Our study revealed that VD (−300 mmHg) significantly increased penile length by 8.2% compared with the controls

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The data reveals patterns so consistent they appear in roughly 85% of patients who complete treatment